Stephanie Chung, M.B.B.S.
- Assistant Clinical Investigator: Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch
- Co-Director: Metabolic Clinical Research Unit, Cores and Support Services
Clinical Trials
Open studies conducted by NIDDK Principal Investigators appear below. Study statuses may include the following:
- Open: Recruiting - Currently recruiting participants and open to everyone who meets eligibility criteria.
- Open: Active, Not Recruiting - Participants are receiving an intervention or being examined, however new participants are not being recruited or enrolled.
- Open: Enrolling by Invitation - People in a particular population were selected in advance and invited to participate. The study is not open to everyone who meets the eligibility criteria.
- Open: Available for Expanded Access - Patients who are not participants in the clinical study may be able to gain access to the drug, biologic, or medical device being studied.
Studies Seeking Patients
Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes
Background:
The pill metformin treats diabetes. But it does not work for all youth, especially
African-Americans. The injectable Liraglutide treats type 2 diabetes in adults. Researchers
want to understand how these drugs work and if they decrease excess sugar made by the liver
in youth with type 2 diabetes.
Objective:
To test if using liraglutide and metformin are better than just metformin for decreasing
excess sugar produced by the liver in African-American youth with type 2 diabetes.
Eligibility:
African-Americans ages 12-21 with type 2 diabetes
Design:
Visit 1: Participants will be screened with medical history, physical exam, and blood and
urine tests.
Participants will stop taking diabetes medicines for 1 week. They will learn how to check
blood sugars at home twice a day.
Visit 2: Overnight at the clinic. Participants will have:
Vital signs taken.
Pregnancy test.
A thin plastic tube (IV catheter) be inserted in each forearm by needle.
Blood drawn several times after drinking a sweet drink.
X-ray of total body fat.
Urine and stool collected.
Breath tests while wearing a clear hood for up to 45 minutes.
For several hours, participants can have only water. At 4 a.m. they will get sugar and fat
with nonradioactive isotopes in one IV. Blood will be collected. Every 30 minutes from 9 a.m.
to 2 p.m., they will drink small amounts of a shake and have blood drawn.
Participants will be randomly assigned to take either both study drugs daily or just
metformin daily.
Visits 3 4: Participants will bring their blood sugar records and have blood tests.
Visit 5, after 3 months: Repeat of visit 2....
The trial is Open with a status of Recruiting.
Investigator: Stephanie T Chung, M.D.
Referral Contacts: Email: Stephanie T Chung, M.D. Phone: (240) 479-8137