Understanding perturbed immunoregulation in diseases of autoimmunity and manipulating the balance between inflammatory and regulatory immune responses.

Select Publications

Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells.
Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B.
Nat Immunol (2022 Jan) 23:62-74. Abstract/Full Text
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.
Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, Sexton JZ, Alysandratos KD, Kotton DN, Pittaluga S, Bibby J, Niyonzima N, Olson MR, Kordasti S, Portilla D, Wobus CE, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M.
Sci Immunol (2021 Apr 7) 6. Abstract/Full Text
View More Publications

Lab Members

Members of the Immunoregulation lab 2022

Top to bottom, left to right: Dhaneshwar Kumar, Daniel Chauss, Tilo Feiwald, Luis Trujillo-Ochoa, Maurice Fluitt, Didier Portilla, Ilayda Sen, Jianping Ma, Ben Afzali, Md Tajmul*
* collaborating post-doctoral fellow from the Kazemian lab, Purdue University

View Our Lab Members