Understanding perturbed immunoregulation in diseases of autoimmunity and manipulating the balance between inflammatory and regulatory immune responses.

Select Publications

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.
Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, Sexton JZ, Alysandratos KD, Kotton DN, Pittaluga S, Bibby J, Niyonzima N, Olson MR, Kordasti S, Portilla D, Wobus CE, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M.
Sci Immunol (2021 Apr 7) 6. Abstract/Full Text
Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.
Kolev M, West EE, Kunz N, Chauss D, Moseman EA, Rahman J, Freiwald T, Balmer ML, Lötscher J, Dimeloe S, Rosser EC, Wedderburn LR, Mayer-Barber KD, Bohrer A, Lavender P, Cope A, Wang L, Kaplan MJ, Moutsopoulos NM, McGavern D, Holland SM, Hess C, Kazemian M, Afzali B, Kemper C.
Immunity (2020 Mar 17) 52:513-527.e8. Abstract/Full Text
View More Publications

Lab Members

Members of the Immunoregulation lab 2020.
 
Top to bottom, left to right: Daniel Chauss, Ben Afzali, Felipe Lopes de Assis*, Jianping Ma, Tilo Freiwald, Nardos Cheru, Maurice Fluitt, Jorge Luis Trujillo-Ochoa, Didier Portilla, Dhaneshwar Kumar
* collaborating post-doctoral fellow from the B cell Immunology Section, Laboratory of Immunoregulation, NIAID
View Our Lab Members