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NIH: National Institute of Diabetes and Digestive and Kidney Diseases NIH: National Institute of Diabetes and Digestive and Kidney Diseases
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  6. Section on mRNA Regulation & Translation

Section on mRNA Regulation & Translation

of the Laboratory of Biochemistry & Genetics

Nicholas Guydosh
A group of scientists interested in the mechanism of the ribosome and how changes in translation alter gene expression in diseases.
About Our Research

Select Publications

Stalled translation on transcripts cleaved by RNase L activates signaling important for innate immunity.
Karasik A, Jones GD, Guydosh NR.
RNA (2026 May 18) 32:945-961. Abstract/Full Text
Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response.
Karasik A, Lorenzi HA, DePass AV, Guydosh NR.
Cell Rep (2024 Jun 25) 43:114287. Abstract/Full Text
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Lab Members

The Guydosh Lab
View Our Lab Members
Last Reviewed January 2024