G protein-coupled receptors and beta-arrestins; Mutant mouse models; Identification of novel targets for the therapy of diabetes and obesity
Select Publications
- G(12/13)-mediated signaling stimulates hepatic glucose production and has a major impact on whole body glucose homeostasis.
- Pittala S, Haspula D, Cui Y, Yang WM, Kim YB, Davis RJ, Wing A, Rotman Y, McGuinness OP, Inoue A, Wess J.
- Nat Commun (2024 Nov 19) 15:9996. Abstract/Full Text
- Activation of Gs signaling in mouse enteroendocrine K cells greatly improves obesity- and diabetes-related metabolic deficits.
- Oteng AB, Liu L, Cui Y, Gavrilova O, Lu H, Chen M, Weinstein LS, Campbell JE, Lewis JE, Gribble FM, Reimann F, Wess J.
- J Clin Invest (2024 Oct 22) 134. Abstract/Full Text
Last Reviewed February 2025