Synthetic Bioactive Molecules Section

Using synthetic organic chemistry to create new molecules with unique biological activities.

Select Publications

RNA detection on a microfluidic platform using Thyclotides.
Amarasekara H, Lehman R, Sangsari PR, Morgan NY, O'Farrell B, Appella DH.
Sens Actuators Rep (2026 Jun) 11. Abstract/Full Text
Sustained mucosal delivery of SAMT-247 via an intravaginal ring reduces the risk of SIV(mac251) acquisition in vaccinated macaques.
Rahman MA, Woode EK, Moss JA, Bissa M, Gunawardana M, Gutowska A, Schifanella L, Silva de Castro I, Brown S, Stamos JD, Sarkis S, Robello M, Castonguay AE, Butkyavichene I, Pise-Masison CA, Choo-Wosoba H, Doster M, Alilin AN, Killoran KE, Kramer J, Breed MW, Cardozo T, Appella DH, Baum MM, Franchini G.
Cell Rep Med (2026 Jul 21) 7:102877. Abstract/Full Text
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Last Reviewed February 2025