Section Chief: Karen Usdin, Ph.D.
Lab News
2022
Work continued in 2021 despite the pandemic
Typical weekly lab meeting in 2021 thanks to COVID-19. Hot on the heels of our first efforts with gene knockouts (Carson!) and base-editing (Bruce!) using CRISPR-Cas9 technology in 2020 which demonstrated that all 3 MutL proteins were required for expansion and that the nuclease activity of MutLɣ was essential, Nan…