Gene Structure and Disease Section

of the Laboratory of Cell and Molecular Biology

The Usdin lab studies the Repeat Expansion Diseases, a group of neurological/neurodevelopmental disorders caused by instability of a disease-specific microsatellite.

Select Publications

FAN1's protection against CGG repeat expansion requires its nuclease activity and is FANCD2-independent.
Zhao X, Lu H, Usdin K.
Nucleic Acids Res (2021 Nov 18) 49:11643-11652. Abstract/Full Text
All three mammalian MutL complexes are required for repeat expansion in a mouse cell model of the Fragile X-related disorders.
Miller CJ, Kim GY, Zhao X, Usdin K.
PLoS Genet (2020 Jun) 16:e1008902. Abstract/Full Text
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Lab Members

Usdin Lab 2022
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