J. Rafael Gorospe, M.D., Ph.D.
Responsibilities & Activities
I primarily administer a portfolio of grants focused on (1) clinical trials related to the diagnosis, prevention, or treatment of prediabetes and type 2 diabetes (T2D) in adults, and (2) clinical studies and trials focused on understanding the pathogenesis, prevention, and treatment of peripheral neuropathy in people with diabetes (T1D and T2D). These portfolios include clinical studies of pharmacologic agents and non-pharmacologic interventions designed to alter the course and improve clinical outcomes for individuals with T2D and painful diabetic peripheral neuropathy. Also included are mechanistic clinical trials focused on understanding the mechanisms of action of treatments for the prevention and treatment of T2D. Additionally, I administer a post-bacalaureate research education program designed to support educational activities that encourage individuals in the biomedical and behavioral sciences, to pursue further studies or careers in research focused on diabetes, endocrinology, and metabolic diseases.
Research Programs
- Clinical Research in Type 2 Diabetes
- Research Training and Career Development
- Centers for Diabetes Translational Research
Research Programs
Clinical Research in Type 2 Diabetes
Progression and treatment of type 2 diabetes in children and adults. Dissemination and Implementation science. Community engaged research methodologies.
Diabetes Centers
Enhancing and extending the effectiveness of diabetes research by encouraging collaboration among investigators from relevant disciplines.
Diabetes: Treatment, Prevention, & Complications
The Diabetes: Treatment, Prevention, and Complications Program supports both basic and clinical studies aimed at addressing the prevention, treatment and pathophysiology of type 1 and type 2 diabetes across the lifespan.
Endocrinology & Hormone Signaling
Hormone and nutrient sensing by the central nervous system, and coordination of energy homeostasis with the stress and reproductive axes in the brain.
Committees & Working Groups
- DEM Training and Career Development Program Committee, Member
- All of Us Liaison Coordinating Team, Member
- NIH HIV and Aging Working Group, Member
Select Experience
Senior Science Advisor, NIH Office of AIDS Research, 2020-2023
Program Director/Medical Officer, NIH-NIGMS, 2011-2020
Program Director/Medical Officer, NIH-NCRR, 2008-2011
Assistant Professor of Pediatrics, George Washington University, Children’s National Medical Center, 2000-2007