Diabetes Centers

Enhancing and extending the effectiveness of diabetes research by encouraging collaboration among investigators from relevant disciplines.

NIDDK Program Staff

Funding for Diabetes Centers

NIDDK’s Diabetes Centers program supports extramural research institutions that have established an existing base of high-quality, diabetes-related research. The program supports and enhances interdisciplinary research in diabetes but does not directly fund major research projects; rather, it provides core resources to enhance the efficiency, productivity, and interdisciplinary cooperation of Center investigators conducting research in diabetes and related areas of endocrinology and metabolism. NIDDK funds Diabetes Centers via P30.

Current Schedule of Review

Centers are funded on the following review schedule:

  • Centers for Diabetes Translation Research: funding opportunity announcements are published once every 5 years. See CDTR application resources.
  • Diabetes Research Centers: funding opportunity announcements are published three times every 5 years. See DRC application resources.

Resources and Services Available from Diabetes Centers

NIDDK Diabetes Centers generate investigative resources that are available to the broader research community. Centers also provide short-term enrichment activities, as well as pilot and feasibility programs that fund small research grants designed to generate preliminary data for larger grant applications.

For more information about each Diabetes Center’s aims, shared resources, pilot and feasibility programs, enrichment programs, and activities, please visit their websites:

Diabetes Research Centers (DRCs)

The DRCs promote new discoveries and enhance scientific progress through support of cutting-edge basic and clinical research related to the etiology and complications of diabetes, with the goal of rapidly translating research findings into novel strategies for the prevention, treatment and cure of diabetes and related conditions.  DRCs are intended to improve the quality and multidisciplinary nature of research on diabetes and related endocrinology and metabolism research by providing shared access to specialized technical resources and expertise and by creating an environment that supports important and innovative research.  DRCs are expected to raise awareness and interest in fundamental and clinical diabetes research at their institutions, as well as locally, regionally, and nationally.

  • Albert Einstein-Mount Sinai Diabetes Center
    • Research Aims: Investigations primarily target the minority and other served under populations prevalent among the residents of the Bronx and Manhattan, adjacent Westchester county, and other boroughs comprising New York City. The primary research efforts encompass both type 1 (T1DM) and type 2 (T2DM) diabetes and related metabolic defects.
    • Activities & Services
      • Cores
        • Animal Physiology Core
        • Biomarker and Analytical Research Core (BARC)
        • The Human Islet & Adenovirus Core (HIAC)
        • Stable Isotope & Metabolomics Core
        • Translational Research Core
      • Pilot and Feasibility Program
        •  Supports
          • New investigators with interests in diabetes or related metabolic and endocrine disorders, including junior investigators shifting from mentor-based research to an independent career. Meritorious applications from new investigators receive priority for funding.
          • Established faculty in other areas who wish to apply their expertise to diabetes research.
          • Diabetes Center members who wish to explore a new area of research that constitutes a substantive departure from their on-going work.
  • Boston Area
    • Research Aims: A consortium of laboratory-based and clinical investigators whose efforts are directed toward addressing many of the major research questions bearing on the etiology, pathogenesis, treatment and cure of type 1 and type 2 diabetes, and their associated microvascular and atherosclerotic complications.
    • Activities & Services
      • Cores
        • Cell Biology and Morphology
        • Metabolic Physiology
        • Molecular Biology
        • Pancreatic Islet
        • Transgenic
      • Pilot and Feasibility Program
        • Supports research in Diabetes and its complications.
  • Columbia University
    • Research Aims: The DRC provides a central support structure to foster collaboration among investigators working in the areas of diabetes, immunology, transplantation, obesity and arteriosclerosis/lipid research and supports their activities by providing shared core resources, funding for pilot/feasibility studies and a common intellectual environment.
    • Activities & Services
      • Cores
        • Hormone & Metabolite
        • Flow Cytometry
        • Histopathology
        • Animal Phenotyping
      • Pilot and Feasibility Program
        • Supports research projects related to diabetes.
  • Johns Hopkins University/University of Maryland
    • Research Aims: Strives to understand the causes of both type 1 and 2 diabetes and promotes translational research that is aimed at reducing the burden of these diseases in the U.S.
    • Activities & Services  
      • Cores
        • Cell Biology Core
        • Integrated Physiology Core
        • Gene Editing Core
        • Molecular and Translational Genomics Core
        • Health and Populations Science Core
      • Pilot & Feasibility Program
  • Joslin Diabetes Center - Harvard Medical School
    • Research Aims: The mission of the Joslin Diabetes Center has been to care for people with diabetes, and conduct research to provide new knowledge about diabetes and its complications that will lead to new treatments, prevention and/or cure of these disorders.    
    •  Activities & Services
      • Cores
        • Advanced Genomic and Genetic Cores
        • Advanced Microscopy Core
        • Animal Physiology Core
        • Bioinformatics Core
        • Enrichment Core
        • Flow Cytometry Core
        • Induced Pluripotent Stem Cell Core
      • Pilot & Feasibility Study
        • Enhance research into the pathogenesis, treatments and potential cures for all types of diabetes and their complications more generally.
  • University of Alabama at Birmingham
    • Research Aims: The center focuses on developing new methods to treat, prevent, and ultimately cure diabetes and its complications.  The DRC supports the areas of animal physiology, human biology and intervention and translational research.
    • Activities & Services
      • Cores
        • Animal Physiology Core (APC)
        • Bioanalytical REDOX Biology Core (BARB)
        • Human Physiology Core (HPC)
        • Interventions and Translation Core (ITC)
      • Pilot and Feasibility Program
        • The P&F program will foster new research programs in diabetes and support a broad base of basic, clinical, translational, and prevention and control projects.
  • UCSD-UCLA
    • Research Aims: The center fosters research in the prevention and treatment of diabetes and endocrine diseases and their complications and ultimately to improves the lives of endocrine patients.
    • Activities & Services
      • Cores
        • Transgenic and Knockout Mouse
        • Metabolic and Molecular Physiology
        • Transcriptional Genomics
        • Human Genetics
        • Novel Target Identification and Assay Development Core
      • Pilot and Feasibility Program
        • The DRC P&F mechanism will fund innovative new projects that will explore the feasibility of novel testable concepts and enhance the endocrine/diabetes research scope within the institutions.
  • UCSF
    • Research Aims: The research components of the UCSF DRC include the following four areas:
      • Islet Biology Program
      • Obesity & Metabolism Program
      • Autoimmunity & Inflammation Program
      • Translation Program
    • Activities & Services
      • Cores
        • Islet Production Core
        • Mouse Metabolism Core
        • Cytometry & Cell Sorting Core
        • Microscopy Core
        • Mouse Genetics Core
        • Lentiviral RNAi Core
      • Pilot and Feasibility Program
  • University of Chicago
    • Research Aims: The University of Chicago Diabetes Research and Training Center promotes multidisciplinary research in diabetes.
    • Activities & Services
      • Cores
        • Islet Cell Biology Core
        • Molecular Biology and Genetics Core Laboratory
        • Animals Models and Physiology Core
      • Pilot and Feasibility Program
        • Supports new investigators in diabetes research as well as established investigators in other fields to conduct novel research related to diabetes.
  • University of Michigan
    • Research Aims: The goal of the MDRC is to establish, promote, and enhance multidisciplinary and collaborative basic biomedical and clinical research among member investigators studying diabetes, its complications, and related endocrine and metabolic disorders.
    • Activities & Services
      • Cores
        • Animal Phenotyping
        • Clinical Core
        • Molecular Genetics
        • Morphology & Image Analysis
      • Pilot and Feasibility Program
        • Research may be in areas of basic biomedical science, behavioral, clinical, epidemiologic or health services research, or in areas related to the development of methodologies for training patients and health care professionals.
  • University of Pennsylvania
    • Research Aims: Supports research in diabetes and endocrinology via Scientific Cores, a Pilot and Feasibility Grant Program, and a series of seminars, retreats and other activities that facilitate communication and collaboration of DRC investigators while keeping them abreast of the latest discoveries in diabetes and endocrinology.
    • Activities & Services
      • Cores
        • Functional Genomics Core
        • Metabolomics Core
        • Islet Cell Biology Core
        • Mouse Phenotyping Core
        • Radioimmunoassy/Biomarker Core
        • Transgenic and Chimeric Mouse Core
        • Viral Vector Core
      • Pilot and Feasibility Program
        • The P&F program is particularly directed at new investigators and established investigators new to diabetes research. Established diabetes investigators pursuing high impact/high risk projects or projects that are a significant departure from their usual work are also eligible for support under the DRC P&F program. Applications are welcome from basic, clinical and translational investigators.
  • University of Washington
    • Research Aims: Facilitating and enhancing diabetes research to find a cure to diabetes.
    • Activities & Services
      • Cores
        • Cell Function Analysis Core
        • Cellular and Molecular Imaging Core
        • Human Studies Core
        • Quantitative and Functional Proteomics Core
        • Viral Vector and Transgenic Mouse Core
      • Pilot and Feasibility Program
        • Intended to develop new research in the area of diabetes and its complications at the University of Washington.
  • Vanderbilt University
    • Research Aims: Facilitating the discovery, application, and translation of scientific knowledge to improve the lives of people with diabetes.
    • Activities & Services
      • Cores
        • Activities & Services Cores Cell Imaging Shared Resource (CISR)
        • Hormone Assay & Analytical Services Core
        • Islet Procurement & Analysis Core
        • Metabolic Physiology Shared Resource (MPSR)
        • Transgenic / ES Cell Shared Resource (TMESCSR)
        • Vanderbilt Diet, Body Composition and Metabolism Core
      • Pilot and Feasibility Program
     
  • Washington University
    • Research Aims: Our long-term goal is the development of new preventive strategies and therapies aimed at improving the lives of Americans with diabetes and those at risk for diabetes and related metabolic disorders.
    • Activities & Services
      • Cores
        • Diabetes Models Phenotyping Core
        • Immunoassay Core - Immunology of Type 1 Diabetes
        • Mass Spectrometry Core
        • Morphology & Metabolic Analysis Core
        • Transgenic & ES Cell Core
      • Pilot and Feasibility Program
  • Yale University
    • Research Aims: The scope of the research activities of the membership is very broad, ranging from basic molecular biology to whole body clinical physiology in patients with diabetes.
    • Activities & Services
      • Cores
        • Cell Biology Core
        • Clinical Metabolism Core
        • Diabetes Translational Core
        • Physiology Core
        • Molecular Genetics Core
      • Pilot and Feasibility Program
        • Priority will be given to new collaborative investigations.

Centers for Diabetes Translation Research (CDTRs)

The CDTRs support and enhance type II translation research (e.g., moving from efficacy to testing effectiveness in real world practice and communities and dissemination and implementation science) related to diabetes prevention and treatment. CDTRs are intended to enhance the efficiency, productivity, and multidisciplinary nature of diabetes translation research through shared access to specialized technical expertise and resources.  CDTRs expertise includes intervention adaptation and refinement, development of measures, techniques, processes, methods, and practices related to diabetes translation research. CDTRs provide core services and consultation at their local institution but also serve as resources regionally and nationally.

  • Albert Einstein College of Medicine    Website available soon.       
  • Emory University    Website available soon. 
  • Kaiser Foundation Research Institute
    • Research Aims: This Center addresses three core areas to improve diabetes care:
      • health care disparities
      • diabetes and obesity prevention
      • health information technology interventions
    • Activities & Services
      • Cores
        • Diabetes and Obesity Prevention
        • Health Care Disparities
        • Health Information Technology
        • CA State Resource Program
  • University of Chicago
    • Research Aims: Our mission is to improve the lives of people with diabetes and people at risk for diabetes through innovative, high-impact research. We seek to prevent diabetes, improve the quality and value of diabetes care, and empower patients and communities.
    • Activities & Services
      • Cores
        • Health Disparities and Community Based Participatory Research Core
        • Outcomes Improvement
        • Quantitative Analysis
      • Pilot and Feasibility Program
        • Projects utilizing methods of health services research, public health research, community-based participatory research, cost-effectiveness research and behavioral intervention research are prioritized.
  • University of Colorado
    • Research Aims: The mission for the Centers for American Indian and Alaska Native Health (CAIANH) is to promote the health and well-being of American Indians and Alaska Natives, of all ages, by pursuing research, training, continuing education, technical assistance, and information dissemination within a biopsychosocial framework that recognizes the unique cultural contexts of this special population.
  • University of Michigan
    • Research Aims: The MCDTR focuses on research to better translate interventions that have clearly demonstrated efficacy into real-world populations, health care settings, and communities.
    • Activities & Services
      • Cores
        • Methods and Measurement
        • Intervention and Technology Research
        • MCDTR and UNC-Chapel Hill Peer Support
      • Pilot and Feasibility Program
        • Research may be in areas of basic biomedical science, behavioral, clinical, epidemiologic or health services research, or in areas related to the development of methodologies for training patients and health care professionals.
  • Vanderbilt University
    • Research Aims: The aim of the Vanderbilt Center for Diabetes Translation Research is to improve prevention and treatment of diabetes and/or obesity by promoting research that supports implementation, dissemination, and sustained use of effective interventions or approaches that improve the health of individuals with diabetes of obesity.
    • Activities & Services
      • Cores
        • Translational Methods Core
        • Community Engagement Cre
        • Technology Core
        • Community Outreach & Health Disparities (COHD)
      • Pilot and Feasibility Program
  • Washington University at St. Louis
    • Research Aims: Our long-term goal is the development of new preventive strategies and therapies aimed at improving the lives of Americans with diabetes and those at risk for diabetes and related metabolic disorders.
    • Activities & Services
      • Cores
        • Diabetes Models Phenotyping Core
        • Immunoassay Core - Immunology of Type 1 Diabetes
        • Mass Spectrometry Core
        • Morphology & Metabolic Analysis Core
        • Transgenic & ES Cell Core
      • Pilot and Feasibility Program


Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

  • Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
  • NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
  • NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.

Related Links

Additional Research Programs

Research Training

Funding Eligibility by Career Level arrow graphic

NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.

Learn about NIDDK Research Training Programs

Diversity

Diversity Programs

The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.

Learn about NIDDK Diversity Programs

Small Business

Small Business Programs

NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs support innovative research conducted by small businesses that has the potential for commercialization.

Learn about NIDDK Small Business Programs

Human Subjects Research

Human Subjects Research

NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.

Learn about Human Subjects Research

Translational Research

Translational Research process graphic

NIDDK provides funding opportunities and resources to encourage translation of basic discoveries into novel therapeutics.

Learn about NIDDK Translational Research Opportunities

Meetings & Events

  • NIH Common Fund

    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.

  • Planning to Apply? Register Early

    Registration is required at eRA Commons and grants.gov and can take 4 weeks.