Seeking to understand the biology of sphingolipids with the goal of developing therapies for the diseases of sphingolipid metabolism.
Select Publications
- Reactivation of mTOR signaling slows neurodegeneration in a lysosomal sphingolipid storage disease.
- Zhu H, Lee YT, Byrnes C, Angina J, Springer DA, Tuymetova G, Kono M, Tifft CJ, Proia RL.
- Neurobiol Dis (2025 Jan) 204:106760. Abstract/Full Text
- Deletion of Gba in neurons, but not microglia, causes neurodegeneration in a Gaucher mouse model.
- Duffy HBD, Byrnes C, Zhu H, Tuymetova G, Lee YT, Platt FM, Proia RL.
- JCI Insight (2024 Nov 8) 9. Abstract/Full Text
Last Reviewed August 2024