Human Disease Section

Select Publications

Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4.

Stephenson RA, Sepulveda J, Johnson KR, Lita A, Gopalakrishnan J, Acri DJ, Beilina A, Cheng L, Yang LG, Root JT, Ward ME, Combs C, Skarnes WC, Cookson MR, Shih HY, Larion M, Rebeck GW, Narayan PS.

Cell Rep (2025 Jul 22) 44:115961. Abstract/Full Text

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia.

Sienski G, Narayan P, Bonner JM, Kory N, Boland S, Arczewska AA, Ralvenius WT, Akay L, Lockshin E, He L, Milo B, Graziosi A, Baru V, Lewis CA, Kellis M, Sabatini DM, Tsai LH, Lindquist S.

Sci Transl Med (2021 Mar 3) 13. Abstract/Full Text

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