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  6. Molecular Recognition Section

Molecular Recognition Section

of the Laboratory of Bioorganic Chemistry

Kenneth Jacobson.
Using chemistry to discover new pharmacological tool compounds and translational candidate molecules, to investigate the role of purinergic signaling in health and disease.
About Our Research

Select Publications

Structure of the human dopamine transporter and mechanisms of inhibition.
Srivastava DK, Navratna V, Tosh DK, Chinn A, Sk MF, Tajkhorshid E, Jacobson KA, Gouaux E.
Nature (2024 Aug) 632:672-677. Abstract/Full Text
Bitopic A(3) Adenosine Receptor Molecular Probes: Positive Allosteric Modulation and Noncanonical Activation.
Kurma SH, Pavan M, Wan TC, Pradhan B, López-Cano M, Ciruela F, Gao ZG, Auchampach JA, Jacobson KA.
J Med Chem (2025 Oct 9) 68:20717-20740. Abstract/Full Text
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Lab Members

Staff of the Molecular Recognition Section

Staff of the Molecular Recognition Section

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Research Materials
Last Reviewed February 2025