Conducting translational and basic studies on immune responses to viruses, in particular those that affect the liver, and their regulation by the gastrointestinal microbiome.

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Naturalized immune responses are stable over years in a colony of laboratory mice with wild-derived microbiota.
Oh JH, Hild B, Yoshida T, Badger JH, Seishima J, McCulloch JA, Jung MK, Azar S, Trinchieri G, Rehermann B.
Immunity (2025 Sep 9) 58:2305-2319.e5. Abstract/Full Text
Neonatal exposure to a wild-derived microbiome protects mice against diet-induced obesity.
Hild B, Dreier MS, Oh JH, McCulloch JA, Badger JH, Guo J, Thefaine CE, Umarova R, Hall KD, Gavrilova O, Rosshart SP, Trinchieri G, Rehermann B.
Nat Metab (2021 Aug) 3:1042-1057. Abstract/Full Text
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Lab Members

Immunology Section in front of National Institutes of Health Building 1 on September 20, 2024. From left to right: Alexis Moore, Keisuke Fukutomi, Sabitree Shahi, Shahar Azar, Barbara Rehermann, Ji Hoon Oh, Jun Seishima.

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Last Reviewed October 2024