Conducting translational and basic studies on immune responses to viruses, in particular those that affect the liver, and their regulation by the gastrointestinal microbiome.

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Laboratory mice born to wild mice have natural microbiota and model human immune responses.
Rosshart SP, Herz J, Vassallo BG, Hunter A, Wall MK, Badger JH, McCulloch JA, Anastasakis DG, Sarshad AA, Leonardi I, Collins N, Blatter JA, Han SJ, Tamoutounour S, Potapova S, Foster St Claire MB, Yuan W, Sen SK, Dreier MS, Hild B, Hafner M, Wang D, Iliev ID, Belkaid Y, Trinchieri G, Rehermann B.
Science (2019 Aug 2) 365. Abstract/Full Text
Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.
Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B.
Cell (2017 Nov 16) 171:1015-1028.e13. Abstract/Full Text
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Lab Members

Immunology Section, front row from left: Benedikt Hild, Helenie Kefalakes, Kaleb Bogale, Cody Stein; back row from left: Stephan Rosshart, Ashli Hunter, Barbara Rehermann, Matthew Dreier and Akira Nishio. Photo taken in Bethesda, Md. on June 4, 2018
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