We study mechanisms of risk and resilience to neurodegenerative diseases.

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PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4.
Narayan P, Sienski G, Bonner JM, Lin YT, Seo J, Baru V, Haque A, Milo B, Akay LA, Graziosi A, Freyzon Y, Landgraf D, Hesse WR, Valastyan J, Barrasa MI, Tsai LH, Lindquist S.
Cell Rep (2020 Oct 6) 33:108224. Abstract/Full Text
Combating neurodegenerative disease with chemical probes and model systems.
Narayan P, Ehsani S, Lindquist S.
Nat Chem Biol (2014 Nov) 10:911-20. Abstract/Full Text
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