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The NIH intramural research program has shifted all non-mission-critical laboratory operations to a maintenance phase in order to promote physical distancing and diminished transmission risk of COVID-19. Effective Monday, March 23, 2020, only mission-critical functions within NIH research laboratories will be supported.

Genetics of Early Development

of the Laboratory of Biochemistry and Genetics

Andy Golden, Ph.D.

Section Chief

andyg@nih.gov

Modeling rare human monogenic diseases in the nematode C. elegans.

About Our Research

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Localized TWIST1 and TWIST2 basic domain substitutions cause four distinct human diseases that can be modeled in Caenorhabditis elegans.: Kim S, Twigg SRF, Scanlon VA, Chandra A, Hansen TJ, Alsubait A, Fenwick AL, McGowan SJ, Lord H, Lester T, Sweeney E, Weber A, Cox H, Wilkie AOM, Golden A, Corsi AK.; Hum Mol Genet (2017 Jun 1) 26:2118-2132. Abstract/Full Text
From phenologs to silent suppressors: Identifying potential therapeutic targets for human disease.: Golden A.; Mol Reprod Dev (2017 Nov) 84:1118-1132. Abstract/Full Text

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