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NIH: National Institute of Diabetes and Digestive and Kidney Diseases NIH: National Institute of Diabetes and Digestive and Kidney Diseases 75 years: 1950-2025 75 years: 1950-2025
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Cell Biochemistry Section

John Hanover.
Employing diverse genetic and biochemical tools to understand mechanisms of nutrient sensing and nuclear-cytoplasmic regulation.
About Our Research

Select Publications

Nutrient-responsive O-GlcNAcylation dynamically modulates the secretion of glycan-binding protein galectin 3.
Mathew MP, Abramowitz LK, Donaldson JG, Hanover JA.
J Biol Chem (2022 Mar) 298:101743. Abstract/Full Text
Cytosolic O-GlcNAcylation and PNG1 maintain Drosophila gut homeostasis by regulating proliferation and apoptosis.
Na HJ, Abramowitz LK, Hanover JA.
PLoS Genet (2022 Mar) 18:e1010128. Abstract/Full Text
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Lab Members

Group of people in winter clothing standing in front of a blooming cherry blossom tree.
From left to right: John Hanover, Agata Steenackers, Marcy Comly, Lara Abramowitz, Ilhan Akan, Dan Konzman, Hyun jin Na, Joshua Dawson, Jeffrey Boakye, Mohit Matthew.
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Research Materials
Last Reviewed March 2025