A selection of recent and significant publications can be viewed below.

Higher fasting plasma FGF21 concentration is associated with lower ad libitum soda consumption in humans.
Basolo A, Hollstein T, Shah MH, Walter M, Krakoff J, Votruba SB, Piaggi P.
Am J Clin Nutr (2021 Oct 4) 114:1518-1522. Abstract/Full Text
Reduced adaptive thermogenesis during acute protein-imbalanced overfeeding is a metabolic hallmark of the human thrifty phenotype.
Hollstein T, Basolo A, Ando T, Krakoff J, Piaggi P.
Am J Clin Nutr (2021 Oct 4) 114:1396-1407. Abstract/Full Text
Metabolic Characterization of Meat, Fish, and Soda Intake in Males: Secondary Results from a Randomized Inpatient Pilot Study.
Mitchell CM, Piaggi P, O'Brien DM, Krakoff J, Votruba SB.
Obesity (Silver Spring) (2021 Jun) 29:995-1002. Abstract/Full Text
The carbon isotope ratios of nonessential amino acids identify sugar-sweetened beverage (SSB) consumers in a 12-wk inpatient feeding study of 32 men with varying SSB and meat exposures.
Johnson JJ, Shaw PA, Oh EJ, Wooller MJ, Merriman S, Yun HY, Larsen T, Krakoff J, Votruba SB, O'Brien DM.
Am J Clin Nutr (2021 May 8) 113:1256-1264. Abstract/Full Text
Urinary Dopamine Excretion Rate Decreases during Acute Dietary Protein Deprivation and Is Associated with Increased Plasma Pancreatic Polypeptide Concentration.
Basolo A, Hollstein T, Walter M, Krakoff J, Piaggi P.
Nutrients (2021 Apr 8) 13. Abstract/Full Text
Reduced metabolic efficiency in sedentary eucaloric conditions predicts greater weight regain in adults with obesity following sustained weight loss.
Hollstein T, Heinitz S, Basolo A, Krakoff J, Votruba SB, Piaggi P.
Int J Obes (Lond) (2021 Apr) 45:840-849. Abstract/Full Text
Lower insulin clearance is associated with increased risk of type 2 diabetes in Native Americans.
Shah MH, Piaggi P, Looker HC, Paddock E, Krakoff J, Chang DC.
Diabetologia (2021 Apr) 64:914-922. Abstract/Full Text
Reduced brown adipose tissue activity during cold exposure is a metabolic feature of the human thrifty phenotype.
Hollstein T, Vinales K, Chen KY, Cypess AM, Basolo A, Schlögl M, Krakoff J, Piaggi P.
Metabolism (2021 Apr) 117:154709. Abstract/Full Text
Reduced Albumin Concentration Predicts Weight Gain and Higher Ad Libitum Energy Intake in Humans.
Basolo A, Ando T, Chang DC, Hollstein T, Krakoff J, Piaggi P, Votruba S.
Front Endocrinol (Lausanne) (2021) 12:642568. Abstract/Full Text
Assessing established BMI variants for a role in nighttime eating behavior in robustly phenotyped Southwestern American Indians.
Köroğlu Ç, Gluck ME, Traurig M, Votruba SB, Krakoff J, Stinson EJ, Chen P, Bogardus C, Piaggi P, Baier LJ.
Eur J Clin Nutr (2020 Dec) 74:1718-1724. Abstract/Full Text
Is Dietary Nonadherence Unique to Obesity and Weight Loss? Results From a Randomized Clinical Trial.
Stinson EJ, Piaggi P, Votruba SB, Venti C, Lovato-Morales B, Engel S, Krakoff J, Gluck ME.
Obesity (Silver Spring) (2020 Nov) 28:2020-2027. Abstract/Full Text
Exome Sequencing Identifies A Nonsense Variant in DAO Associated With Reduced Energy Expenditure in American Indians.
Piaggi P, Köroğlu Ç, Nair AK, Sutherland J, Muller YL, Kumar P, Hsueh WC, Kobes S, Shuldiner AR, Kim HI, Gosalia N, Van Hout CV, Jones M, Knowler WC, Krakoff J, Hanson RL, Bogardus C, Baier LJ.
J Clin Endocrinol Metab (2020 Nov 1) 105. Abstract/Full Text
Early adaptive thermogenesis is a determinant of weight loss after six weeks of caloric restriction in overweight subjects.
Heinitz S, Hollstein T, Ando T, Walter M, Basolo A, Krakoff J, Votruba SB, Piaggi P.
Metabolism (2020 Sep) 110:154303. Abstract/Full Text
Metabolic Responses to 24-Hour Fasting and Mild Cold Exposure in Overweight Individuals Are Correlated and Accompanied by Changes in FGF21 Concentration.
Hollstein T, Heinitz S, Ando T, Rodzevik TL, Basolo A, Walter M, Chang DC, Krakoff J, Piaggi P.
Diabetes (2020 Jul) 69:1382-1388. Abstract/Full Text
Thigh Adipocyte Size is Inversely Related to Energy Intake and Respiratory Quotient in Healthy Women.
Basolo A, Shah MH, Parthasarathy V, Parrington S, Walter M, Votruba SB, Krakoff J, Piaggi P, Chang DC.
Obesity (Silver Spring) (2020 Jun) 28:1129-1140. Abstract/Full Text
Metabolic Factors Determining the Susceptibility to Weight Gain: Current Evidence.
Hollstein T, Piaggi P.
Curr Obes Rep (2020 Jun) 9:121-135. Abstract/Full Text
Recharacterizing the Metabolic State of Energy Balance in Thrifty and Spendthrift Phenotypes.
Hollstein T, Basolo A, Ando T, Votruba SB, Walter M, Krakoff J, Piaggi P.
J Clin Endocrinol Metab (2020 May 1) 105. Abstract/Full Text
Higher Urinary Dopamine Concentration is Associated with Greater Ad Libitum Energy Intake in Humans.
Basolo A, Ando T, Hollstein T, Votruba SB, Krakoff J, Piaggi P.
Obesity (Silver Spring) (2020 May) 28:953-961. Abstract/Full Text
Reply to Mantha OL et al.
O'Brien DM, Votruba SB.
Am J Clin Nutr (2020 May 1) 111:1110-1111. Abstract/Full Text
Chronic psychosocial and financial burden accelerates 5-year telomere shortening: findings from the Coronary Artery Risk Development in Young Adults Study.
Cabeza de Baca T, Prather AA, Lin J, Sternfeld B, Adler N, Epel ES, Puterman E.
Mol Psychiatry (2020 May) 25:1141-1153. Abstract/Full Text
Urinary Norepinephrine Is a Metabolic Determinant of 24-Hour Energy Expenditure and Sleeping Metabolic Rate in Adult Humans.
Hollstein T, Basolo A, Ando T, Votruba SB, Krakoff J, Piaggi P.
J Clin Endocrinol Metab (2020 Apr 1) 105. Abstract/Full Text
Hydration biomarkers and copeptin: relationship with ad libitum energy intake, energy expenditure, and metabolic fuel selection.
Chang DC, Basolo A, Piaggi P, Votruba SB, Krakoff J.
Eur J Clin Nutr (2020 Jan) 74:158-166. Abstract/Full Text
Associations of plasma, RBCs, and hair carbon and nitrogen isotope ratios with fish, meat, and sugar-sweetened beverage intake in a 12-wk inpatient feeding study.
Votruba SB, Shaw PA, Oh EJ, Venti CA, Bonfiglio S, Krakoff J, O'Brien DM.
Am J Clin Nutr (2019 Dec 1) 110:1306-1315. Abstract/Full Text
Sleep debt: the impact of weekday sleep deprivation on cardiovascular health in older women.
Cabeza de Baca T, Chayama KL, Redline S, Slopen N, Matsushita F, Prather AA, Williams DR, Buring JE, Zaslavsky AM, Albert MA.
Sleep (2019 Oct 9) 42. Abstract/Full Text
Metabolic response to fasting predicts weight gain during low-protein overfeeding in lean men: further evidence for spendthrift and thrifty metabolic phenotypes.
Hollstein T, Ando T, Basolo A, Krakoff J, Votruba SB, Piaggi P.
Am J Clin Nutr (2019 Sep 1) 110:593-604. Abstract/Full Text
Effects of Short-Term Fasting and Different Overfeeding Diets on Thyroid Hormones in Healthy Humans.
Basolo A, Begaye B, Hollstein T, Vinales KL, Walter M, Santini F, Krakoff J, Piaggi P.
Thyroid (2019 Sep) 29:1209-1219. Abstract/Full Text
Financial strain and ideal cardiovascular health in middle-aged and older women: Data from the Women's health study.
Cabeza de Baca T, Burroughs Peña MS, Slopen N, Williams D, Buring J, Albert MA.
Am Heart J (2019 Sep) 215:129-138. Abstract/Full Text
Cognitive dietary restraint, disinhibition, and hunger are associated with 24-h energy expenditure.
Stinson EJ, Graham AL, Thearle MS, Gluck ME, Krakoff J, Piaggi P.
Int J Obes (Lond) (2019 Jul) 43:1456-1465. Abstract/Full Text
Fasting glucagon-like peptide 1 concentration is associated with lower carbohydrate intake and increases with overeating.
Basolo A, Heinitz S, Stinson EJ, Begaye B, Hohenadel M, Piaggi P, Krakoff J, Votruba SB.
J Endocrinol Invest (2019 May) 42:557-566. Abstract/Full Text
Core body temperature, energy expenditure, and epinephrine during fasting, eucaloric feeding, and overfeeding in healthy adult men: evidence for a ceiling effect for human thermogenic response to diet.
Vinales KL, Begaye B, Thearle MS, Krakoff J, Piaggi P.
Metabolism (2019 May) 94:59-68. Abstract/Full Text
Metabolic Determinants of Weight Gain in Humans.
Piaggi P.
Obesity (Silver Spring) (2019 May) 27:691-699. Abstract/Full Text
A low resting metabolic rate in late childhood is associated with weight gain in adolescence.
Hohenadel MG, Hollstein T, Thearle M, Reinhardt M, Piaggi P, Salbe AD, Krakoff J.
Metabolism (2019 Apr) 93:68-74. Abstract/Full Text
Reduced plasma albumin predicts type 2 diabetes and is associated with greater adipose tissue macrophage content and activation.
Chang DC, Xu X, Ferrante AW Jr, Krakoff J.
Diabetol Metab Syndr (2019) 11:14. Abstract/Full Text
FGF21 Is a Hormonal Mediator of the Human "Thrifty" Metabolic Phenotype.
Vinales KL, Begaye B, Bogardus C, Walter M, Krakoff J, Piaggi P.
Diabetes (2019 Feb) 68:318-323. Abstract/Full Text
Food Insecurity is Associated with Maladaptive Eating Behaviors and Objectively Measured Overeating.
Stinson EJ, Votruba SB, Venti C, Perez M, Krakoff J, Gluck ME.
Obesity (Silver Spring) (2018 Dec) 26:1841-1848. Abstract/Full Text
Endocannabinoid Anandamide Mediates the Effect of Skeletal Muscle Sphingomyelins on Human Energy Expenditure.
Heinitz S, Basolo A, Piomelli D, Krakoff J, Piaggi P.
J Clin Endocrinol Metab (2018 Oct 1) 103:3757-3766. Abstract/Full Text
Predictive Accuracy of Surrogate Indices for Hepatic and Skeletal Muscle Insulin Sensitivity.
Muniyappa R, Tella SH, Sortur S, Mszar R, Grewal S, Abel BS, Auh S, Chang DC, Krakoff J, Skarulis MC.
J Endocr Soc (2019 Jan 1) 3:108-118. Abstract/Full Text
Lack of partner impacts newborn health through maternal depression: A pilot study of low-income immigrant Latina women.
Cabeza de Baca T, Wojcicki JM, Epel ES, Adler NE.
Midwifery (2018 Sep) 64:63-68. Abstract/Full Text
Exenatide has a pronounced effect on energy intake but not energy expenditure in non-diabetic subjects with obesity: A randomized, double-blind, placebo-controlled trial.
Basolo A, Burkholder J, Osgood K, Graham A, Bundrick S, Frankl J, Piaggi P, Thearle MS, Krakoff J.
Metabolism (2018 Aug) 85:116-125. Abstract/Full Text
Norepinephrine and T4 Are Predictors of Fat Mass Gain in Humans With Cold-Induced Brown Adipose Tissue Activation.
Begaye B, Piaggi P, Thearle MS, Haskie K, Walter M, Schlögl M, Bonfiglio S, Krakoff J, Vinales KL.
J Clin Endocrinol Metab (2018 Jul 1) 103:2689-2697. Abstract/Full Text
One-Hour Plasma Glucose Compared With Two-Hour Plasma Glucose in Relation to Diabetic Retinopathy in American Indians.
Paddock E, Looker HC, Piaggi P, Knowler WC, Krakoff J, Chang DC.
Diabetes Care (2018 Jun) 41:1212-1217. Abstract/Full Text
Response of skeletal muscle UCP2-expression during metabolic adaptation to caloric restriction.
Heinitz S, Piaggi P, Yang S, Bonfiglio S, Steel J, Krakoff J, Votruba SB.
Int J Obes (Lond) (2018 Jun) 42:974-984. Abstract/Full Text
Deviations in energy sensing predict long-term weight change in overweight Native Americans.
Basolo A, Votruba SB, Heinitz S, Krakoff J, Piaggi P.
Metabolism (2018 May) 82:65-71. Abstract/Full Text
High Fat and Sugar Consumption During Ad Libitum Intake Predicts Weight Gain.
Stinson EJ, Piaggi P, Ibrahim M, Venti C, Krakoff J, Votruba SB.
Obesity (Silver Spring) (2018 Apr) 26:689-695. Abstract/Full Text
Depressive symptoms and poorer performance on the Stroop Task are associated with weight gain.
Stinson EJ, Krakoff J, Gluck ME.
Physiol Behav (2018 Mar 15) 186:25-30. Abstract/Full Text
Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage.
Heinitz S, Basolo A, Piaggi P, Piomelli D, Jumpertz von Schwartzenberg R, Krakoff J.
J Clin Endocrinol Metab (2018 Mar 1) 103:1077-1087. Abstract/Full Text
Cycling Efficiency During Incremental Cycle Ergometry After 24 Hours of Overfeeding or Fasting.
Vinales KL, Schlögl M, Reinhardt M, Thearle MS, Krakoff J, Piaggi P.
Obesity (Silver Spring) (2018 Feb) 26:368-377. Abstract/Full Text
Decline in the acute insulin response in relationship to plasma glucose concentrations.
Heinitz S, Piaggi P, Bogardus C, Krakoff J.
Diabetes Metab Res Rev (2018 Feb) 34. Abstract/Full Text
Energy expenditure in the etiology of human obesity: spendthrift and thrifty metabolic phenotypes and energy-sensing mechanisms.
Piaggi P, Vinales KL, Basolo A, Santini F, Krakoff J.
J Endocrinol Invest (2018 Jan) 41:83-89. Abstract/Full Text
Energy Expenditure and Hormone Responses in Humans After Overeating High-Fructose Corn Syrup Versus Whole-Wheat Foods.
Ibrahim M, Bonfiglio S, Schlögl M, Vinales KL, Piaggi P, Venti C, Walter M, Krakoff J, Thearle MS.
Obesity (Silver Spring) (2018 Jan) 26:141-149. Abstract/Full Text