A selection of recent and significant publications can be viewed below.

Risk Factors for Delta Hepatitis in a North American Cohort: Who Should Be Screened?
Da BL, Rahman F, Lai WC, Kleiner DE, Heller T, Koh C.
Am J Gastroenterol (2021 Jan 1) 116:206-209. Abstract/Full Text
HLA-B*35:01 and Green Tea Induced Liver Injury.
Hoofnagle JH, Bonkovsky HL, Phillips EJ, Li YJ, Ahmad J, Barnhart H, Durazo F, Fontana RJ, Gu J, Khan I, Kleiner DE, Koh C, Rockey DC, Seeff LB, Serrano J, Stolz A, Tillmann HL, Vuppalanchi R, Navarro VJ, Drug-Induced Liver Injury Network..
Hepatology (2020 Sep 5) Abstract/Full Text
A Viral Exposure Signature Defines Early Onset of Hepatocellular Carcinoma.
Liu J, Tang W, Budhu A, Forgues M, Hernandez MO, Candia J, Kim Y, Bowman ED, Ambs S, Zhao Y, Tran B, Wu X, Koh C, Surana P, Liang TJ, Guarnera M, Mann D, Rajaure M, Greten TF, Wang Z, Yu H, Wang XW.
Cell (2020 Jul 23) 182:317-328.e10. Abstract/Full Text
Coronavirus Disease-19 Has Come Home to Roost in Gastroenterology.
Koh C, Liang TJ.
Gastroenterology (2020 Jul) 159:36-38. Abstract/Full Text
Spontaneous Clearance of Chronic Delta Hepatitis.
Kapuria D, Ben Yakov G, Koh C, Heller T.
Hepatology (2020 May) 71:1873-1875. Abstract/Full Text
Hepatocellular Carcinoma Where You Least Expect It.
Rubin JN, Gilman CAL, Gasmi B, Stern WR, Hernandez JM, Koh C.
Am J Gastroenterol (2020 Apr 10) Abstract/Full Text
Vibration-controlled transient elastography for the detection of cirrhosis in chronic hepatitis D infection.
Da BL, Surana P, Takyar V, Kleiner DE, Heller T, Koh C.
J Viral Hepat (2020 Apr) 27:428-436. Abstract/Full Text
United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts.
Oketch-Rabah HA, Roe AL, Rider CV, Bonkovsky HL, Giancaspro GI, Navarro V, Paine MF, Betz JM, Marles RJ, Casper S, Gurley B, Jordan SA, He K, Kapoor MP, Rao TP, Sherker AH, Fontana RJ, Rossi S, Vuppalanchi R, Seeff LB, Stolz A, Ahmad J, Koh C, Serrano J, Low Dog T, Ko R.
Toxicol Rep (2020) 7:386-402. Abstract/Full Text
The Delta-4 fibrosis score (D4FS): A novel fibrosis score in chronic hepatitis D.
Da BL, Surana P, Kleiner DE, Heller T, Koh C.
Antiviral Res (2020 Feb) 174:104691. Abstract/Full Text
Portal Pressure in Noncirrhotic Portal Hypertension: To Measure or Not to Measure.
Da BL, Surana P, Kapuria D, Vittal A, Levy E, Kleiner DE, Koh C, Heller T.
Hepatology (2019 Dec) 70:2228-2230. Abstract/Full Text
Cryo-EM structure of the bacterial Ton motor subcomplex ExbB-ExbD provides information on structure and stoichiometry.
Celia H, Botos I, Ni X, Fox T, De Val N, Lloubes R, Jiang J, Buchanan SK.
Commun Biol (2019) 2:358. Abstract/Full Text
Chronic hepatitis delta: A state-of-the-art review and new therapies.
Gilman C, Heller T, Koh C.
World J Gastroenterol (2019 Aug 28) 25:4580-4597. Abstract/Full Text
Longitudinal effects of Nucleos(t)ide analogue therapy in chronic hepatitis B patients and the utility of non-invasive fibrosis markers during treatment: A single-center experience for up to 17 years.
Surana P, Kapuria D, Broadwell C, Wright EC, Takyar V, Kleiner DE, Ghany MG, Ben-Yakov G, Heller T, Liang TJ, Koh C.
Antiviral Res (2019 Aug) 168:61-67. Abstract/Full Text
Hepatic Manifestations of Cystic Fibrosis.
Sakiani S, Kleiner DE, Heller T, Koh C.
Clin Liver Dis (2019 May) 23:263-277. Abstract/Full Text
Pathogenesis of and New Therapies for Hepatitis D.
Koh C, Heller T, Glenn JS.
Gastroenterology (2019 Jan) 156:461-476.e1. Abstract/Full Text
Endocannabinoid Anandamide Mediates the Effect of Skeletal Muscle Sphingomyelins on Human Energy Expenditure.
Heinitz S, Basolo A, Piomelli D, Krakoff J, Piaggi P.
J Clin Endocrinol Metab (2018 Oct 1) 103:3757-3766. Abstract/Full Text
Hrg1 promotes heme-iron recycling during hemolysis in the zebrafish kidney.
Zhang J, Chambers I, Yun S, Phillips J, Krause M, Hamza I.
PLoS Genet (2018 Sep) 14:e1007665. Abstract/Full Text
Nutrient-Driven O-GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution.
Krause MW, Love DC, Ghosh SK, Wang P, Yun S, Fukushige T, Hanover JA.
Front Endocrinol (Lausanne) (2018) 9:521. Abstract/Full Text
Exenatide has a pronounced effect on energy intake but not energy expenditure in non-diabetic subjects with obesity: A randomized, double-blind, placebo-controlled trial.
Basolo A, Burkholder J, Osgood K, Graham A, Bundrick S, Frankl J, Piaggi P, Thearle MS, Krakoff J.
Metabolism (2018 Aug) 85:116-125. Abstract/Full Text
Spleen and Liver Volumetrics as Surrogate Markers of Hepatic Venous Pressure Gradient in Patients With Noncirrhotic Portal Hypertension.
Etzion O, Takyar V, Novack V, Gharib AM, Canales R, Adebogun A, Matsumoto E, Eccleston JL, Kleiner DE, Rosenzweig SD, Gunay-Aygun M, Uzel G, Fuss I, Childs R, Holland SM, Levy EB, Liang TJ, Heller T, Koh C.
Hepatol Commun (2018 Aug) 2:919-928. Abstract/Full Text
Association of Hepatic Steatosis With Subclinical Atherosclerosis: Systematic Review and Meta-Analysis.
Kapuria D, Takyar VK, Etzion O, Surana P, O'Keefe JH, Koh C.
Hepatol Commun (2018 Aug) 2:873-883. Abstract/Full Text
Norepinephrine and T4 Are Predictors of Fat Mass Gain in Humans With Cold-Induced Brown Adipose Tissue Activation.
Begaye B, Piaggi P, Thearle MS, Haskie K, Walter M, Schlögl M, Bonfiglio S, Krakoff J, Vinales KL.
J Clin Endocrinol Metab (2018 Jul 1) 103:2689-2697. Abstract/Full Text
One-Hour Plasma Glucose Compared With Two-Hour Plasma Glucose in Relation to Diabetic Retinopathy in American Indians.
Paddock E, Looker HC, Piaggi P, Knowler WC, Krakoff J, Chang DC.
Diabetes Care (2018 Jun) 41:1212-1217. Abstract/Full Text
Response of skeletal muscle UCP2-expression during metabolic adaptation to caloric restriction.
Heinitz S, Piaggi P, Yang S, Bonfiglio S, Steel J, Krakoff J, Votruba SB.
Int J Obes (Lond) (2018 Jun) 42:974-984. Abstract/Full Text
Deviations in energy sensing predict long-term weight change in overweight Native Americans.
Basolo A, Votruba SB, Heinitz S, Krakoff J, Piaggi P.
Metabolism (2018 May) 82:65-71. Abstract/Full Text
Liver disease in patients with cystic fibrosis.
Kamal N, Surana P, Koh C.
Curr Opin Gastroenterol (2018 May) 34:146-151. Abstract/Full Text
High Fat and Sugar Consumption During Ad Libitum Intake Predicts Weight Gain.
Stinson EJ, Piaggi P, Ibrahim M, Venti C, Krakoff J, Votruba SB.
Obesity (Silver Spring) (2018 Apr) 26:689-695. Abstract/Full Text
Optimizing lonafarnib treatment for the management of chronic delta hepatitis: The LOWR HDV-1 study.
Yurdaydin C, Keskin O, Kalkan Ç, Karakaya F, Çalişkan A, Karatayli E, Karatayli S, Bozdayi AM, Koh C, Heller T, Idilman R, Glenn JS.
Hepatology (2018 Apr) 67:1224-1236. Abstract/Full Text
Depressive symptoms and poorer performance on the Stroop Task are associated with weight gain.
Stinson EJ, Krakoff J, Gluck ME.
Physiol Behav (2018 Mar 15) 186:25-30. Abstract/Full Text
Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage.
Heinitz S, Basolo A, Piaggi P, Piomelli D, Jumpertz von Schwartzenberg R, Krakoff J.
J Clin Endocrinol Metab (2018 Mar 1) 103:1077-1087. Abstract/Full Text
The ColM Family, Polymorphic Toxins Breaching the Bacterial Cell Wall.
Ghequire MGK, Buchanan SK, De Mot R.
mBio (2018 Feb 13) 9. Abstract/Full Text
Cycling Efficiency During Incremental Cycle Ergometry After 24 Hours of Overfeeding or Fasting.
Vinales KL, Schlögl M, Reinhardt M, Thearle MS, Krakoff J, Piaggi P.
Obesity (Silver Spring) (2018 Feb) 26:368-377. Abstract/Full Text
Energy expenditure in the etiology of human obesity: spendthrift and thrifty metabolic phenotypes and energy-sensing mechanisms.
Piaggi P, Vinales KL, Basolo A, Santini F, Krakoff J.
J Endocrinol Invest (2018 Jan) 41:83-89. Abstract/Full Text
Energy Expenditure and Hormone Responses in Humans After Overeating High-Fructose Corn Syrup Versus Whole-Wheat Foods.
Ibrahim M, Bonfiglio S, Schlögl M, Vinales KL, Piaggi P, Venti C, Walter M, Krakoff J, Thearle MS.
Obesity (Silver Spring) (2018 Jan) 26:141-149. Abstract/Full Text
Autoantibodies against PFDN2 are associated with an increased risk of type 2 diabetes: A case-control study.
Chang DC, Piaggi P, Hanson RL, Knowler WC, Bogardus C, Krakoff J.
Diabetes Metab Res Rev (2017 Nov) 33. Abstract/Full Text
Specific skeletal muscle sphingolipid compounds in energy expenditure regulation and weight gain in Native Americans of Southwestern heritage.
Heinitz S, Piaggi P, Vinales KL, Basolo A, Spranger J, Piomelli D, Krakoff J, Jumpertz von Schwartzenberg R.
Int J Obes (Lond) (2017 Oct) 41:1585-1593. Abstract/Full Text
One-hour and two-hour postload plasma glucose concentrations are comparable predictors of type 2 diabetes mellitus in Southwestern Native Americans.
Paddock E, Hohenadel MG, Piaggi P, Vijayakumar P, Hanson RL, Knowler WC, Krakoff J, Chang DC.
Diabetologia (2017 Sep) 60:1704-1711. Abstract/Full Text
Insertion of proteins and lipopolysaccharide into the bacterial outer membrane.
Botos I, Noinaj N, Buchanan SK.
Philos Trans R Soc Lond B Biol Sci (2017 Aug 5) 372. Abstract/Full Text
A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians.
Piaggi P, Masindova I, Muller YL, Mercader J, Wiessner GB, Chen P, SIGMA Type 2 Diabetes Consortium., Kobes S, Hsueh WC, Mongalo M, Knowler WC, Krakoff J, Hanson RL, Bogardus C, Baier LJ.
Diabetes (2017 Aug) 66:2284-2295. Abstract/Full Text
A Novel Approach to Predict 24-Hour Energy Expenditure Based on Hematologic Volumes: Development and Validation of Models Comparable to Mifflin-St Jeor and Body Composition Models.
Chang DC, Piaggi P, Krakoff J.
J Acad Nutr Diet (2017 Aug) 117:1177-1187. Abstract/Full Text
Adult-onset cystic fibrosis liver disease: Diagnosis and characterization of an underappreciated entity.
Koh C, Sakiani S, Surana P, Zhao X, Eccleston J, Kleiner DE, Herion D, Liang TJ, Hoofnagle JH, Chernick M, Heller T.
Hepatology (2017 Aug) 66:591-601. Abstract/Full Text
Inter-organ signalling by HRG-7 promotes systemic haem homeostasis.
Sinclair J, Pinter K, Samuel T, Beardsley S, Yuan X, Zhang J, Meng K, Yun S, Krause M, Hamza I.
Nat Cell Biol (2017 Jul) 19:799-807. Abstract/Full Text
The nematode homologue of Mediator complex subunit 28, F28F8.5, is a critical regulator of C. elegans development.
Kostrouchová M, Kostrouch D, Chughtai AA, Kaššák F, Novotný JP, Kostrouchová V, Benda A, Krause MW, Saudek V, Kostrouchová M, Kostrouch Z.
PeerJ (2017) 5:e3390. Abstract/Full Text
A Genetic Analysis of the Caenorhabditis elegans Detoxification Response.
Fukushige T, Smith HE, Miwa J, Krause MW, Hanover JA.
Genetics (2017 Jun) 206:939-952. Abstract/Full Text
Structural snapshots of the β-barrel assembly machinery.
Bakelar J, Buchanan SK, Noinaj N.
FEBS J (2017 Jun) 284:1778-1786. Abstract/Full Text
Pharmacokinetics and pharmacodynamics modeling of lonafarnib in patients with chronic hepatitis delta virus infection.
Canini L, Koh C, Cotler SJ, Uprichard SL, Winters MA, Han MAT, Kleiner DE, Idilman R, Yurdaydin C, Glenn JS, Heller T, Dahari H.
Hepatol Commun (2017 Jun) 1:288-292. Abstract/Full Text
Two-Partner Secretion: Combining Efficiency and Simplicity in the Secretion of Large Proteins for Bacteria-Host and Bacteria-Bacteria Interactions.
Guérin J, Bigot S, Schneider R, Buchanan SK, Jacob-Dubuisson F.
Front Cell Infect Microbiol (2017) 7:148. Abstract/Full Text
The β-barrel assembly machinery in motion.
Noinaj N, Gumbart JC, Buchanan SK.
Nat Rev Microbiol (2017 Apr) 15:197-204. Abstract/Full Text
The obese brain as a heritable phenotype: a combined morphometry and twin study.
Weise CM, Piaggi P, Reinhardt M, Chen K, Savage CR, Krakoff J, Pleger B.
Int J Obes (Lond) (2017 Mar) 41:458-466. Abstract/Full Text
Complications of percutaneous liver biopsy with Klatskin needles: a 36-year single-centre experience.
Takyar V, Etzion O, Heller T, Kleiner DE, Rotman Y, Ghany MG, Fryzek N, Williams VH, Rivera E, Auh S, Liang TJ, Hoofnagle JH, Koh C.
Aliment Pharmacol Ther (2017 Mar) 45:744-753. Abstract/Full Text