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Jose Serrano, M.D., Ph.D.

Photo of Jose Serrano
Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis; Drug Induced Liver Injury; Clinical Research on GI Diseases

Responsibilities & Activities

As program director for projects studying liver, gastrointestinal, neuroendocrine, and pancreas processes, I oversee a research portfolio on the major diseases affecting the liver, pancreas, and the gastrointestinal tract. Providing scientific, programmatic, and fiscal management of basic research and clinical studies, my work supports advancement of the Division’s goals, which are: to find the primary causes of liver, pancreatic, and gastrointestinal diseases; to characterize the factors that contribute to their progression; and to develop interventions for their treatment and prevention.

I manage a basic science portfolio on exocrine pancreas and GI neuroendocrine pathophysiology and diseases as well as in liver toxicity due to medication and dietary supplements. I also serve as Project Scientist or Program Offial in several research networks and large clinical studies like The Drug Induced Liver Injury Network (DILIN) 2003-to present. The Gastroparesis Clinical Research Consortium (GpCRC) 2010-present. The MEthotrexate Response in Treatment of UC (MERIT-UC) 2011-present. The Predicting Response to Standardized Pediatric Colitis Therapy 2012-present. The Stent vs. Indomethacin for preventing post-ERCP pancreatitis (SVI) 2013-present. The L. reuteri for Pediatric Diarrhea in Peru: Growth, Enteropathy, and Microbiota study (PRIDEC-Peru) 2014-present. The Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC) 2015-present. The SpHincterotomy in Acute Recurrent Pancreatitis with Pancreas Divisum Trial (SHARP) 2016-present. The Results of ERCP in SPhincter of Oddi Dysfunction Study (ReSPOND) 2017-present. The APpendicitis in Pediatrics: Exploring the Nonoperative Debate Trial (APPEND-X) 2017-present the Liver Tissue and Cell Distribution System.

Research Programs

Acute & Chronic Pancreatitis
Research on the etiology and pathogenesis of acute and chronic pancreatitis.

Digestive Diseases Clinical Research & Epidemiology
Patient-oriented clinical research and epidemiology research in digestive diseases.

Endocrine Tumors of the Pancreas
Research on endocrine tumors of the pancreas.

Gastrointestinal Neuroendocrinology
NIDDK research programs on gastrointestinal neuroendocrinology.

Gastrointestinal Physiology, Development, & Epithelial Biology
Basic, clinical, and translational research on GI development, diseases, and disorders.

Hereditary & Pediatric Disorders of the Pancreas
Research on hereditary and pediatric disorders of the pancreas.

Liver Clinical Research & Epidemiology
Patient-oriented clinical research and epidemiological research in liver diseases.

Pancreas Basic Research & Development
Research on the development, structure, function, and diseases of the exocrine pancreas.

Pancreas Clinical Research & Epidemiology
Patient-oriented clinical research and epidemiology research on diseases of the exocrine pancreas.

Translational & Basic Liver Disease Research
Translational and basic research on liver physiology and pathophysiology and liver diseases.

Committees & Working Groups

  • NIDDK’s Translation Working Group, Member
  • NIDDK Clinical Studies Working Group, Member
  • NIH Knowledge Management for Disease Coding Project, Member