Hereditary & Pediatric Disorders of the Pancreas
Research on hereditary and pediatric disorders of the pancreas.
The Hereditary and Pediatric Disorders of the Pancreas program supports research on the genetic factors contributing to the etiology of pancreatic diseases and on childhood disorders of the pancreas. Particular areas of interest include understanding genetic factors and their interactions with exogenous insults, with respect to pathogenesis, complications, and natural history of pancreatitis and other pancreatic disorders. Studies involve genetic screenings that identify gene mutations in candidate genes or their regulatory elements that are associated with pancreatic structural or functional abnormalities. Researchers are focused on the identification of biologic or molecular mechanisms of pancreatic injury associated with the identification of mutant alleles; the generation of novel animal models of pancreatitis or abnormal pancreatic function by expression of mutant genes associated with pancreatic disease; and the identification of other genetic and environmental factors that influence the development and course of pancreatitis in genetically susceptible individuals.
NIDDK Program Staff
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Patient-oriented Research to Mitigate Health Disparities and Lessen the Burden of Chronic Diseases Within the Mission of NIDDK (R01 Clinical Trial Optional)
Gastrointestinal (GI) and Microbiome Explorers: Development of Swallowable Smart Pills or Devices for Precision Nutrition, Microbiome and Digestive Disease Applications (R21/R33 Clinical Trial Required)
Development of Wearable Smart Devices for Continuous Monitoring of Circulating Nutrients, Metabolites and Hormones (R21/R33 Clinical Trial Required)
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)
Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)
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