Liver Clinical Research & Epidemiology
Patient-oriented clinical research and epidemiological research in liver diseases.
The Liver Clinical Research and Epidemiology program supports patient-oriented clinical research in liver diseases. Work in the program examines a wide range of experimental interventions or diagnostics with direct impact on liver disease diagnosis or pathology endpoints.
The program emphasizes research on common and rare liver diseases and supports large clinical research networks. Current and past clinical research networks supported by this program have included: NASH Clinical Research Network, Adult-to-Adult Living Donor Liver Transplantation Cohort Study, Adult Acute Liver Failure Study Group, Pediatric Acute Liver Failure, Drug-Induced Liver Injury Network, Childhood Liver Disease Research and Education Network, Hepatitis B Research Network, Hepatitis C Antiviral Long-term Treatment against Cirrhosis, and Peds C.
NIDDK Program Staff
- Averell H. Sherker, M.D., FRCPC Autoimmune Liver Disease; Acute Liver Failure; Complications of Chronic Liver Disease; Gallbladder and Biliary Diseases; Liver Bioengineering and Biotechnology; Liver Cancer; Liver Transplantation
- Aynur Unalp-Arida M.D., M.Sc., Ph.D. Epidemiology, Clinical Trials, Digestive Diseases, and Nutrition
- Edward Doo, M.D. Fatty Liver Disease; Genetic Liver Disease; HIV and Liver; Pediatric Liver Disease; Viral Hepatitis and Infectious Diseases
- Jose Serrano, M.D., Ph.D. Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis; Drug Induced Liver Injury; Clinical Research on GI Diseases
Recent Funding OpportunitiesView More Recent Funding Opportunities
PHS 2020-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
PHS 2020-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, Clinical Trial Not Allowed)
Mechanistic Studies of the Interaction between SARS-CoV-2/COVID-19 and Diseases and Organ Systems of Interest to NIDDK (R01 Clinical Trial Optional)
View related clinical trials from ClinicalTrials.gov.
Study sections conduct initial peer review of applications in a designated scientific area. Visit the NIH’s Center for Scientific Review website to search for study sections.
NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
- Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
- NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
- NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.
Additional Research Programs
NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.Learn about NIDDK Research Training Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.Learn about NIDDK Diversity Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs support innovative research conducted by small businesses that has the potential for commercialization.Learn about NIDDK Small Business Programs
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.Learn about Human Subjects Research
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries into novel therapeutics.Learn about NIDDK Translational Research Opportunities
Meetings & Workshops
Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.
Providing education and training for the next generation of biomedical and behavioral scientist