Dr. Sherman is a mathematician involved in modeling diabetes and insulin secretion
Patrick Fletcher earned a master's degree in mathematical biology from the University of British Columbia, and a Ph.D. in biomathematics from Florida State University. He came to LBM in 2015 as a post-doctoral fellow, and since 2020 has been a Research Fellow. His research interests include mathematical modeling of cell physiological processes and analysis of biomedical data. Current research projects include modeling of calcium and electrical signaling in anterior pituitary cells and pancreatic beta cells, analysis of time series data from fluorescence video microscopy in beta cells, and analysis of single-cell RNA sequencing data of anterior pituitary cells. For more about his work, see Patrick Fletcher's Website.
Dr. Yang received her Ph.D. in mathematical biology from the University of Florida. She came to LBM in July 2023 as a post-doctoral fellow. Her main interest is in modeling endocrine diseases including thyroid disorders and diabetes. Her current work focuses on modeling different pathways for the pathogenesis of type 2 diabetes and the durable effects of anti-diabetic agents at different disease stages.
Dr. Ha received his Ph. D. in mathematics in 2008 from the New Jersey Institute of Technology under the mentorship of Amit Bose. He was a post-doctoral Visiting Fellow, then a Research Fellow in LBM from 2010 – 2018 and a contractor until 2021. He continues to work closely with LBM as a Special Volunteer and member of the Department of Mathematics at Howard University (see https://math.columbian.gwu.edu/joon-ha). His training was in dynamical systems applied to neuroscience, and at NIH he applied that to studying electrical activity and insulin secretion in pancreatic beta cells. His current work focuses on the mechanisms of diabetes pathogenesis with applications to better screening and treatment.