About Our Research
Our group develops and applies improved NMR methods for the study of macromolecular structure and dynamics including
- methods which provide additional structural constraints for obtaining higher definition of macromolecular structure.
- methods and procedures for facilitating the resonance assignment process.
- methods for a better characterization of internal and overall macromolecular dynamics.
- methods for extending the molecular weight limit of systems that can be studied.
Equipment
Our group is equipped with modern Bruker NMR spectrometers capable of triple resonance and pulsed field gradient experiments, and shares instruments operating at 500 to 800 MHz with the group of G.M. Clore and a 900 MHz spectrometer with other intramural research groups.
Pulse Programs, Hardware, Software, and Servers
We aim to disseminate technology developed in our group as widely as possible. All software and pulse programs with associated contents can be accessed at https://spin.niddk.nih.gov/bax/
Scientific Lectures
Select scientific lectures by Dr. Adriaan Bax and his colleagues are featured below.
- Residual Dipolar Couplings: Theory and Applications, Part 1, Australian and New Zealand Society for Magnetic Resonance (ANZMAG), 2013
- Residual Dipolar Couplings: Theory and Applications, Part 2, ANZMAG, 2013
- Additional ANZMAG Lectures
Research Images

Ribbon Diagram depicting the homo-dimeric catalytic core domain of the HIV1 integrase enzyme

N-terminal fusion domain of hemagglutinin, adopting a helical hairpin structure at neutral pH.

Alpha-synuclein

Ribbon view of the single alpha-helical domain of Myosin-VI

Nuclear Magnetic Resonance (NMR) Spectrometer

Talking could transmit SARS-CoV-2, early NIDDK research suggests

Small saliva droplets can remain airborne more than 10 minutes, NIDDK study shows

Emission of droplets during speech generation visualized using green light