Translational Research: Clinical Development
Clinical evaluation of novel pre-therapeutics involves a highly regulated process by which the agent is carefully tested in clinical populations. The precise design of these studies varies by the nature of the agent, and in the case of repurposed compounds or naturally occurring biologics may involve existing human safety data. Clinical evaluation of compounds is a continuing process involving larger clinical trials through post-marketing monitoring.
Target AssayScreeningHits and
HitHit to LeadLead Series
NIDDK-Specific Funding Opportunities
- RFA-NS-22-034, HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain
- Potential opportunities include ancillary studies to ongoing clinical studies, exploratory/developmental grants, and investigator-initiated multi-center clinical studies.
- NIDDK Central Repository
- NCATS TRND
- Academic Drug Discovery Consortium
- NIDDK Small Business Programs
For more information on NIDDK funding opportunities to support clinical development and testing of new therapeutics, please visit the NIDDK Human Subjects Research page.