Translational Research: Assay Development
The identification and testing of agents acting through a particular target that may modify a disease’s course typically require a set of reliable and reproducible assays to demonstrate the efficacy, selectivity, and potency of the potential therapeutic candidate. Such assays may be used to identify hits from high throughput screening campaigns, refine peptides by molecular panning, or assess in vivo properties of agents.
Target AssayScreeningHits and
HitHit to LeadLead Series
NIDDK-Specific Funding Opportunities
- PA-16-374, Assay Development and Screening to Discover Therapeutic or Imaging Agents for Diseases of Interest to the NIDDK (R01)
- Academic Drug Discovery Consortium
- NIH Molecular Libraries and Imaging
- NIDDK Small Business Programs
For questions regarding this topic, please contact Dr. Aaron Pawlyk.