Erythropoiesis & Hemoglobin
The molecular and cellular biological pathways involved in erythroid cell differentiation.
The Erythropoiesis and Hemoglobin program supports work on the molecular and cellular biological pathways involved in erythroid cell differentiation. This includes not only adult or definitive erythropoiesis (differentiation), but also ontological or primitive erythropoiesis (development). Specific areas of interest include: transcriptional, post-transcriptional, and translational regulation of erythroid-specific genes; mechanisms underlying normal and disordered globin gene regulation; heme biosynthesis and iron metabolism during erythropoiesis; erythroid cell membrane structure and function and the interaction of transport and receptor molecules; erythropoietin receptor signaling and its effects on gene regulation; mechanistic determinants of red blood cell survival; detection of abnormal hemoglobins; development of genetically targeted therapies for sickle cell anemia and thalassemias; and development of clinically applicable approaches for controlling fetal versus adult b-globin gene expression.
NIDDK Program Staff
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NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34 Clinical Trial Optional)
NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Required)
NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Not Allowed)
Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)
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NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
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Additional Research Programs
NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.Learn about NIDDK Research Training Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.Learn about NIDDK Diversity Programs
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