Erythropoiesis & Hemoglobin
The molecular and cellular biological pathways involved in erythroid cell differentiation.
The Erythropoiesis and Hemoglobin program supports work on the molecular and cellular biological pathways involved in erythroid cell differentiation. This includes not only adult or definitive erythropoiesis (differentiation), but also ontological or primitive erythropoiesis (development). Specific areas of interest include: transcriptional, post-transcriptional, and translational regulation of erythroid-specific genes; mechanisms underlying normal and disordered globin gene regulation; heme biosynthesis and iron metabolism during erythropoiesis; erythroid cell membrane structure and function and the interaction of transport and receptor molecules; erythropoietin receptor signaling and its effects on gene regulation; mechanistic determinants of red blood cell survival; detection of abnormal hemoglobins; development of genetically targeted therapies for sickle cell anemia and thalassemias; and development of clinically applicable approaches for controlling fetal versus adult b-globin gene expression.
NIDDK Program Staff
Recent Funding OpportunitiesView More Recent Funding Opportunities
Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)
Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)
NOSI: Academy of Finland (AKA) National Institutes of Health (NIH) Partnership Program
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
Limited Competition: Lasker Clinical Research Scholars Transition Award (R00 Clinical Trial Optional)
View related clinical trials from ClinicalTrials.gov.
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