Erythropoiesis & Hemoglobin
The molecular and cellular biological pathways involved in erythroid cell differentiation.
The Erythropoiesis and Hemoglobin program supports work on the molecular and cellular biological pathways involved in erythroid cell differentiation. This includes not only adult or definitive erythropoiesis (differentiation), but also ontological or primitive erythropoiesis (development). Specific areas of interest include: transcriptional, post-transcriptional, and translational regulation of erythroid-specific genes; mechanisms underlying normal and disordered globin gene regulation; heme biosynthesis and iron metabolism during erythropoiesis; erythroid cell membrane structure and function and the interaction of transport and receptor molecules; erythropoietin receptor signaling and its effects on gene regulation; mechanistic determinants of red blood cell survival; detection of abnormal hemoglobins; development of genetically targeted therapies for sickle cell anemia and thalassemias; and development of clinically applicable approaches for controlling fetal versus adult b-globin gene expression.
NIDDK Program Staff
Recent Funding OpportunitiesView More Recent Funding Opportunities
Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
Education Program on Translational Devices (R25 Clinical Trial Not Allowed)
KUH Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 - Independent Clinical Trial Not Allowed)
NIDDK Partnerships with Professional Societies to Enhance Scientific Workforce Diversity and Promote Scientific Leadership (R25 - Clinical Trial Not Allowed)
HEAL Initiative: Discovery of Biomarkers and Biomarker Signatures to Facilitate Clinical Trials for Pain Therapeutics (UG3/UH3 Clinical Trial Optional)
View related clinical trials from ClinicalTrials.gov.
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Additional Research Programs
NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.Learn about NIDDK Research Training Programs
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