Cystic Fibrosis Research & Translation Centers

Funding for Cystic Fibrosis Research & Translation Centers

The goal of these CF Research and Translation Centers is to support research to develop and test therapies for CF. Centers provide increased, cost effective collaboration among multidisciplinary groups of investigators at institutions or a group of institutions with an established, comprehensive research base in cystic fibrosis.

NIDDK funds Cystic Fibrosis Centers through a P30 mechanism. Please see the CF Application Resources for required tables and addition documentation.

Centers are funded on the following review schedule:

• 3 Centers January Council 2023
• 4 Centers January Council 2020

Resources and Services Available from Cystic Fibrosis Research & Translation Centers

The Cystic Fibrosis Research and Translation Centers provide a variety of research resources to facilitate CF research from basic to the conduct of clinical trials. In addition, there are pilot and feasibility research programs that provide limited funds for early stage investigations.

Cystic Fibrosis Center Sites

The Cystic Fibrosis Research and Translation Centers provide research services for investigators at their sites as well as for other investigators at other regional, national and even international sites. These services are quite varied and include various CF related efforts involving biochemical, cell models, animal models small molecule therapeutic development, gene vectors and clinical applications.

• Research Aims: The UNC CF Center focus includes ion transport physiology, mucin biology, microbiology and animal models.
• Activities & Services
  • UNC CF Center has Cores including preclinical, cell models, mucous biochemistry and clinical translation.
  • Pilot & Feasibility Program

• Research Aims: The UAB CF Center aims are to provide a multi-disciplinary research support for CF basic research and therapy.
• Activities & Services
  • The UAB CF Center maintains Core facilities available for studies of cell biology, ion transport, animal models and translational aspects of CF research.
  • Pilot & Feasibility Program

• Research Aims: The UCSF CF Center focus is to develop novel therapies for cystic fibrosis and to enhance many research projects examining the mechanisms of cystic fibrosis lung disease.
• Activities & Services
  • The UCSF CF Center has Cores including high throughput screening, synthesis, cells and tissues and bioassay.

• Research Aims: The U of W CF Center focus is clinical-translational science in cystic fibrosis (CF), spanning from early drug development to dissemination into the CF community.
• Activities & Services
  • The U of W CF Center has Cores including microbiology, genomics, host response and clinical care.
  • Pilot & Feasibility Program

• Research Aims: The U of Iowa research aims include gene therapy, animal models and CF related diabetes.
• Activities & Services
  • The U of Iowa CF Center has Cores including gene vector, animal models, clinical, comparative pathology, cells and tissue.
  • Pilot & Feasibility Program

• Research Aims: The Georgia CF Center research focus includes CF-related diabetes (CFRD), the impact of CF on nutritional status, gastrointestinal function, liver function, (including CF-related liver disease, CFLD), and metabolism, and the relationship between these complications of CF disease and lifestyle/behavioral choices such as diet, exercise, activity and sleep.
• Activities & Services
  • The Georgia CF Center has Cores including diabetes, GI and Nutrition, clinical research and informatics as well as lifestyle and behavior.
  • Pilot & Feasibility Program

• Research Aims: The Cincinnati Children's CF Center research aims are to strengthen and expand the CF research program at CCHMC with an emphasis on establishing a thematic program of "personalized Medicine for CF".

• NIH Common Fund

  Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.

• Planning to Apply? Register Early

  Registration is required at eRA Commons and grants.gov and can take 4 weeks.