Neurobiology of Obesity
Neurobiology of energy balance and clinical studies on non-homeostatic (extra-hypothalamic) contributions to obesity and diabetes.
The Neurobiology of Obesity and Metabolic Diseases program encompasses research on the regulation of body composition and peripheral metabolism by the brain. Specific areas of support within this area include neurotransmitters, neuropeptides and their receptors involved in regulating feeding behavior, energy sensing, satiety, and energy expenditure; interactions between the brain and peripheral metabolic signals, e.g., insulin, leptin, glucocorticoids, ghrelin; the neural integration of endocrine and metabolic signals; neural plasticity and functional remodeling associated with obesity and metabolic diseases, and the early development of neural networks that control feeding, satiety and peripheral metabolism.
NIDDK Program Staff
- Rajatava Basu, Ph.D. Role of immune system in the pathophysiology of Type 2 Diabetes and diabetes-associated metabolic dysfunction, including the role of chronic & meta-inflammation, microbiome-immune-metabolic crosstalk and neuroinflammation
- Brad Cooke, Ph.D. Developmental Neuroendocrinology, Electrophysiology, and Cognitive Neuroscience
- Diana Cummings, Ph.D. Gut-Brain Interactions in Nutrition and Obesity; Nutrient Sensing; Gastrointestinal Interoception; Neurobiology of Nausea and Vomiting
- Theresa Teslovich Woo, Ph.D. Human behavior, developmental cognitive neuroscience, and brain-based mechanisms involved in obesity and diabetes
Recent Funding OpportunitiesView More Recent Funding Opportunities
Addressing the Impact of Syndemics on the Health of People with HIV and Diseases and Conditions within the Missions of NIDDK and NHLBI (R01 Clinical Trial Optional)
Federated Biobanking resource for the Down Syndrome Cohort Study Program (DS-CDP) across the lifespan for the INCLUDE Project (U24 Clinical Trial Not Allowed)
Down Syndrome Clinical Cohort Coordinating Center (DS-4C) for the INCLUDE Project (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) (U54 Clinical Trial Not Allowed)
NIAID and NIDDK Research Opportunities for New and "At-Risk" Investigators to Promote Workforce Diversity (R01 Clinical Trial Optional)
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity)
View related clinical trials from ClinicalTrials.gov.
Study sections conduct initial peer review of applications in a designated scientific area. Visit the NIH’s Center for Scientific Review website to search for study sections.
NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
- Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
- NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
- NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.
Additional Research Programs
NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.Learn about NIDDK Research Training Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.Learn about NIDDK Diversity Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs support innovative research conducted by small businesses that has the potential for commercialization.Learn about NIDDK Small Business Programs
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.Learn about Human Subjects Research
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries into novel therapeutics.Learn about NIDDK Translational Research Opportunities
Meetings & Workshops
Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.
Providing education and training for the next generation of biomedical and behavioral scientist
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