Kidney Precision Medicine Project

Identifying critical human cells, pathways, and targets for new therapies in acute and chronic kidney diseases.

The NIDDK Kidney Precision Medicine Project (KPMP) aims to ethically obtain and evaluate human kidney biopsies from participants with Acute Kidney Injury (AKI) or Chronic Kidney Disease (CKD), create a kidney tissue atlas, define disease subgroups, and identify critical cells, pathways, and targets for novel therapies. The project will have four distinct, but highly interactive activities: Recruitment Sites, Tissues Interrogation Sites, a Central Hub and a Kidney Tissue Atlas Coordinating Center. Additional technology development in support of the KPMP will be supported by small business programs.

KPMP Activities

View detailed KPMP Structure and Stages (PDF, 503.86 KB) .

Related Links

• Innovative Science Accelerator (ISAC) Program

   

• Kidney Precision Medicine Project (KPMP)

   

• Kidney Precision Medicine Meeting

  2016

• Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Consortium
• Overcoming Barriers in Acute Kidney Injury (AKI)

  2015

• The Kidney Research National Dialogue: gearing up to move forward

  2014

• NIDDK Central Repository
• NIDDK Active Trials in Kidney Disease

  View related clinical trials from ClinicalTrials.gov.

• NIH Study Sections

  Study sections conduct initial peer review of applications in a designated scientific area. Visit the NIH’s Center for Scientific Review website to search for study sections.

Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

• Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
• NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
• NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.

Additional Research Programs

Research Training

NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.

Learn about NIDDK Research Training Programs

Small Business

Small Business Programs

NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs support innovative research conducted by small businesses that has the potential for commercialization.

Learn about NIDDK Small Business Programs

Human Subjects Research

Human Subjects Research

NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.

Learn about Human Subjects Research

Translational Research

NIDDK provides funding opportunities and resources to encourage translation of basic discoveries into novel therapeutics.

Learn about NIDDK Translational Research Opportunities

Meetings & Workshops

2025 NIDDK K Awardees Workshop

Nov. 20 - 21, 2025
North Bethesda, MD

dkNET

Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.

NIH Regional Seminars on Program Funding and Grants Administration

Providing education and training for the next generation of biomedical and behavioral scientist

View all Meetings & Workshops

View all Meetings & Workshops