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Translational & Basic Liver Disease Research

Translational and basic research on liver physiology and pathophysiology and liver diseases.

NIDDK Program Staff

  • Bonnie Burgess-Beusse, Ph.D. Liver cell, molecular and developmental biology; liver regeneration; bile, bilirubin and cholestasis
  • Edward Doo, M.D. Fatty Liver Disease; Genetic Liver Disease; HIV and Liver; Pediatric Liver Disease; Viral Hepatitis and Infectious Diseases
  • Martha Garcia, Ph.D. Mechanisms in drug-induced hepatotoxicity, molecular pathways in metabolic dysfunction-associated steatotic liver disease (MASLD), lipotoxicity.
  • Averell H. Sherker, M.D., FRCPC Autoimmune Liver Disease; Acute Liver Failure; Complications of Chronic Liver Disease; Gallbladder and Biliary Diseases; Liver Bioengineering and Biotechnology; Liver Cancer; Liver Transplantation

Recent Funding Opportunities

View More Recent Funding Opportunities
  1. PAR-24-206

    Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)

  2. NOT-OD-24-078

    Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research

  3. NOT-OD-24-079

    Notice of Special Interest: Womens Health Research

  4. RFA-NS-25-012

    HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)

  5. PAR-24-162

    Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)

View More Recent Funding Opportunities
  • View related clinical trials from ClinicalTrials.gov.

  • Study sections conduct initial peer review of applications in a designated scientific area. Visit the NIH’s Center for Scientific Review website to search for study sections.

  • This online resource provides information on drug-induced liver injury resulting from prescription medications, over-the-counter drugs, and complementary and alternative medicines such as herbals and dietary supplements.

Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

  • Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
  • NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
  • NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.

Additional Research Programs

Research Training

Funding Eligibility by Career Level arrow graphic

NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.

Learn about NIDDK Research Training Programs


Diversity Programs

The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.

Learn about NIDDK Diversity Programs

Small Business

Small Business Programs

NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs support innovative research conducted by small businesses that has the potential for commercialization.

Learn about NIDDK Small Business Programs

Human Subjects Research

Human Subjects Research

NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.

Learn about Human Subjects Research

Translational Research

Translational Research process graphic

NIDDK provides funding opportunities and resources to encourage translation of basic discoveries into novel therapeutics.

Learn about NIDDK Translational Research Opportunities

Meetings & Workshops

  • NIH Common Fund

    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.

  • Planning to Apply? Register Early

    Registration is required at eRA Commons and grants.gov and can take 4 weeks.

Last Reviewed October 2023