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Hemodialysis Opioid Prescription Effort (HOPE) Consortium

Part of NIH’s HEAL initiative, the Hemodialysis Opioid Prescription Effort (HOPE) consortium addresses the prescription of opioid medications in the ESRD hemodialysis population.

NIDDK Participation in NIH’s HEAL

In conjunction with NIH’s HEAL initiative, NIDDK proposed the Hemodialysis Opioid Prescription Effort (HOPE) consortium as a means of addressing pain and opioid use within the U.S. End-Stage Renal Disease (ESRD) hemodialysis program.
The NIDDK will focus on

  • pain in U.S. ESRD hemodialysis patients
  • reduction of chronic opioid prescriptions for the ESRD population
  • behavioral, cognitive, and medical interventions to reduce pain and the number of opioid prescriptions in ESRD hemodialysis patients

About the HOPE Consortium

The HOPE consortium is composed of eight Clinical Centers and a Scientific and Data Research Center. The consortium delivers a pain coping skills intervention and offers buprenorphine to reduce dependence on opioids in selected hemodialysis patients.

Funding Opportunities

NIDDK offers the following funding opportunities for HOPE

HEAL Initiative: Integrated Approach to Pain and Opioid Use in Hemodialysis Patients: The Hemodialysis Opioid Prescription Effort (HOPE) consortium

About NIH’s HEAL initiative

The National Institutes of Health HEAL (Helping to End Addiction Long-term) Initiative is a trans-agency effort focused on improving prevention and treatment strategies for opioid misuse and addiction, and enhancing pain management. Launched in April 2018 with funding from Congress, the opioid HEAL Initiative, brings new hope for people, families, and communities affected by the national public health crisis.

NIDDK Program Staff

Recent Funding Opportunities

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Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

  • Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
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Additional Research Programs

Research Training

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NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.

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Diversity Programs

The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.

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Small Business

Small Business Programs

NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs support innovative research conducted by small businesses that has the potential for commercialization.

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Human Subjects Research

Human Subjects Research

NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.

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Translational Research

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NIDDK provides funding opportunities and resources to encourage translation of basic discoveries into novel therapeutics.

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Meetings & Workshops

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    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.

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Last Reviewed October 2023